What the FDA labels say about taking them together
Elbasvir/grazoprevir and emtricitabine
Elbasvir/grazoprevir's FDA label of March 13, 2026 names emtricitabine in its drug interactions section; the emtricitabine label PlainMeds reads does not name elbasvir/grazoprevir. The elbasvir/grazoprevir label: “Co-administration of cobicistat-containing regimens is not recommended.”
Check it at the source: the elbasvir/grazoprevir FDA label on DailyMed (effective March 13, 2026, Merck Sharp & Dohme LLC); the emtricitabine FDA label on DailyMed (effective December 2, 2025, Gilead Sciences, Inc.).
What does the elbasvir/grazoprevir label say about emtricitabine?
Elbasvir/grazoprevir label, drug interactionsConcomitant Drug Class/Drug Name: Elvitegravir/ cobicistat/ emtricitabine/ tenofovir (disoproxil fumarate or alafenamide); Effect on Concentration ↓ = decrease, ↑ = increase: ↑ EBR ↑ GZR; Clinical Comment: Co-administration of cobicistat-containing regimens is not recommended.
Source: FDA drug label (ZEPATIER), Merck Sharp & Dohme LLC, effective March 13, 2026 (SPL set 164dc02a-9180-426a-b8b5-04ab39d2bbd4), via openFDA; the full label on DailyMed
What does the emtricitabine label say about elbasvir/grazoprevir?
Emtricitabine's label (effective December 2, 2025) does not name elbasvir/grazoprevir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Emtriva), Gilead Sciences, Inc., effective December 2, 2025 (SPL set d6599395-3944-44f9-97f2-e0424c6b6a1f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Elbasvir/grazoprevir | Emtricitabine | |
|---|---|---|
| Labeled for | Hepatitis C | HIV |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | $12.69 per capsule 200 mg capsule |
| Shortage now | A presentation being discontinued | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once