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What the FDA labels say about taking them together

Elagolix and rosuvastatin

Elagolix's FDA label of December 19, 2025 names rosuvastatin in its drug interactions section; the rosuvastatin labels PlainMeds reads (2) do not name elagolix. The elagolix label: “Monitor lipid levels and adjust the dose of rosuvastatin, if necessary.”

Check it at the source: the elagolix FDA label on DailyMed (effective December 19, 2025, AbbVie Inc.); the rosuvastatin FDA label on DailyMed (effective September 4, 2026, ScieGen Pharmaceuticals, Inc.).

What does the elagolix label say about rosuvastatin?

Elagolix label, drug interactions

Concomitant Drug Class/Drug Name: Statins: rosuvastatin; Effect on Plasma Exposure of Concomitant Drug: ↓ rosuvastatin; Clinical Recommendations: Monitor lipid levels and adjust the dose of rosuvastatin, if necessary.

Source: FDA drug label (Orilissa), AbbVie Inc., effective December 19, 2025 (SPL set a86757b3-09c5-fd3b-1223-244e94f50a66), via openFDA; the full label on DailyMed

What does the rosuvastatin label say about elagolix?

Rosuvastatin's label (effective September 4, 2026) and its 1 other brand-application label do not name elagolix in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Rosuvastatin), ScieGen Pharmaceuticals, Inc., effective September 4, 2026 (SPL set ee4933c5-0d97-494d-ac0f-2083e0100836), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

0Elagolix generic labelers
45Rosuvastatin generic labelers
ElagolixRosuvastatin
Labeled forn/aHeart attack and coronary artery disease, High cholesterol, High triglycerides, Stroke prevention
Boxed warningNoNo
Pharmacy cost (NADAC)$43.81 per tablet 150 mg tablet$0.0692 per tablet 40 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?