What the FDA labels say about taking them together
Elafibranor and norgestrel
Elafibranor's FDA label of August 11, 2026 names norgestrel in its drug interactions section; the norgestrel label PlainMeds reads does not name elafibranor. The elafibranor label: “Intervention; Switch to progestin only product containing levonorgestrel/norgestrel, intrauterine system, or effective non-hormonal contraceptives when using hormonal contraceptives during treatment with IQIRVO and for …”
Check it at the source: the elafibranor FDA label on DailyMed (effective August 11, 2026, Ipsen Biopharmaceuticals, Inc.); the norgestrel FDA label on DailyMed (effective August 6, 2026, CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED).
What does the elafibranor label say about norgestrel?
Elafibranor label, drug interactionsIntervention; Switch to progestin only product containing levonorgestrel/norgestrel, intrauterine system, or effective non-hormonal contraceptives when using hormonal contraceptives during treatment with IQIRVO and for at least 3 weeks after last dose [see,, ].
Elafibranor label, warnings and precautionsAdvise females of reproductive potential to avoid use of hormonal contraceptives containing ethinyl estradiol and to use alternative contraception, including progestin-only contraceptives containing levonorgestrel/norgestrel, intrauterine systems, or effective non-hormonal contraceptives during treatment with IQIRVO and for 3 weeks after the last dose of IQIRVO [see Drug Interactions (7.1), Use in Specific Populations (8.3) ].
Source: FDA drug label (IQIRVO), Ipsen Biopharmaceuticals, Inc., effective August 11, 2026 (SPL set d78aa14f-6ec1-4b1d-a4ae-e48658137a25), via openFDA; the full label on DailyMed
What does the norgestrel label say about elafibranor?
Norgestrel's label (effective August 6, 2026) does not name elafibranor in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Daily Oral Contraceptive), NDA017031 (Laboratoire Hra), as published by CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED, effective August 6, 2026 (SPL set 20477912-c1d6-4190-8f6e-00fb122134a1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Elafibranor | Norgestrel | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.549 per tablet 0.075 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once