What the FDA labels say about taking them together
Elafibranor and fenofibrate
Elafibranor's FDA label of August 11, 2026 names fenofibrate in its drug interactions section; the fenofibrate labels PlainMeds reads (3) do not name elafibranor. The elafibranor label: “Clinical impact; Co-administration of IQIRVO with other PPAR-alpha agonists may increase risk of liver injury and muscle injury.”
Check it at the source: the elafibranor FDA label on DailyMed (effective August 11, 2026, Ipsen Biopharmaceuticals, Inc.); the fenofibrate FDA label on DailyMed (effective April 29, 2024, A-S Medication Solutions).
What does the elafibranor label say about fenofibrate?
Elafibranor label, drug interactionsClinical impact; Co-administration of IQIRVO with other PPAR-alpha agonists (e.g., fenofibrate, fenofibric acid) may increase risk of liver injury and muscle injury.
Elafibranor label, warnings and precautionsPatients concomitantly taking peroxisome proliferator-activated receptor-alpha (PPAR-alpha) agonists (e.g., fenofibrate, fenofibric acid) may have an increased risk of muscle injury.
Source: FDA drug label (IQIRVO), Ipsen Biopharmaceuticals, Inc., effective August 11, 2026 (SPL set d78aa14f-6ec1-4b1d-a4ae-e48658137a25), via openFDA; the full label on DailyMed
What does the fenofibrate label say about elafibranor?
Fenofibrate's label (effective April 29, 2024) and its 2 other brand-application labels do not name elafibranor in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Tricor), NDA021656 (Abbvie), as published by A-S Medication Solutions, effective April 29, 2024 (SPL set 84b2af1b-365e-4723-ac5f-bc826ec47772), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Elafibranor | Fenofibrate | |
|---|---|---|
| Labeled for | n/a | High cholesterol, High triglycerides |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.103 per tablet 160 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once