What the FDA labels say about taking them together
Efavirenz and mifepristone
Mifepristone's FDA label of September 25, 2025 names efavirenz in its drug interactions section; the efavirenz label PlainMeds reads does not name mifepristone.
Check it at the source: the efavirenz FDA label on DailyMed (effective March 31, 2024, Cipla USA Inc.); the mifepristone FDA label on DailyMed (effective September 25, 2025, Corcept Therapeutics Incorporated).
What does the efavirenz label say about mifepristone?
Efavirenz's label (effective March 31, 2024) does not name mifepristone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Efavirenz), Cipla USA Inc., effective March 31, 2024 (SPL set 92603fa5-7a2c-4bfb-9a70-aadb4fba952c), via openFDA; the full label on DailyMed
What does the mifepristone label say about efavirenz?
Mifepristone label, drug interactionsDrugs metabolized by CYP2B6: Use of mifepristone should be done with caution with bupropion and efavirenz ( 7.5 ).
Source: FDA drug label (Mifepristone), Corcept Therapeutics Incorporated, effective September 25, 2025 (SPL set 63c068cd-9370-460f-829b-70e8c7ebe91e), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Efavirenz | Mifepristone | |
|---|---|---|
| Labeled for | HIV | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $1.28 per tablet 600 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once