What the FDA labels say about taking them together
Edetate and propofol
Propofol's FDA label of September 11, 2025 names edetate in its warnings and precautions section; the edetate label PlainMeds reads does not name propofol. The propofol label: “DIPRIVAN is a single-dose parenteral product which contains 0.005% disodium edetate (EDTA) to inhibit the rate of growth of microorganisms, for up to 12 hours, in the event of accidental extrinsic contamination.”
Check it at the source: the edetate FDA label on DailyMed (effective February 13, 2025, Rising Pharma Holdings, Inc.); the propofol FDA label on DailyMed (effective September 11, 2025, Fresenius Kabi USA, LLC).
What does the edetate label say about propofol?
Edetate's label (effective February 13, 2025) does not name propofol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Edetate Calcium Disodium), Rising Pharma Holdings, Inc., effective February 13, 2025 (SPL set 710a2c8c-3620-4f6f-b8fc-fb19ab9e9f22), via openFDA; the full label on DailyMed
What does the propofol label say about edetate?
Propofol label, warnings and precautionsDIPRIVAN is a single-dose parenteral product (single patient infusion vial) which contains 0.005% disodium edetate (EDTA) to inhibit the rate of growth of microorganisms, for up to 12 hours, in the event of accidental extrinsic contamination.
Source: FDA drug label (Diprivan), Fresenius Kabi USA, LLC, effective September 11, 2025 (SPL set e3105799-a4b6-f3f4-e6e2-b2b29bbdb538), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Edetate | Propofol | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $0.171 per mL 200 mg/20 mL vial |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once