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What the FDA labels say about taking them together

Droperidol and pimozide

Pimozide's FDA label of August 12, 2026 names droperidol in its drug interactions section; the droperidol label PlainMeds reads does not name pimozide. The pimozide label: “Accordingly, pimozide should not be given with dofetilide, sotalol, quinidine, other Class Ia and III anti-arrhythmics, mesoridazine, thioridazine, chlorpromazine, droperidol, sparfloxacin, gatifloxacin, moxifloxacin …”

Check it at the source: the droperidol FDA label on DailyMed (effective June 8, 2022, Hikma Pharmaceuticals USA Inc.); the pimozide FDA label on DailyMed (effective August 12, 2026, Par Health USA, LLC).

What does the droperidol label say about pimozide?

Droperidol's label (effective June 8, 2022) does not name pimozide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (DROPERIDOL), Hikma Pharmaceuticals USA Inc., effective June 8, 2022 (SPL set d89f33ac-8a6e-49e7-94fb-84e58aad65a8), via openFDA; the full label on DailyMed

What does the pimozide label say about droperidol?

Pimozide label, drug interactions

Accordingly, pimozide should not be given with dofetilide, sotalol, quinidine, other Class Ia and III anti-arrhythmics, mesoridazine, thioridazine, chlorpromazine, droperidol, sparfloxacin, gatifloxacin, moxifloxacin, halofantrine, mefloquine, pentamidine, arsenic trioxide, levomethadyl acetate, dolasetron mesylate, probucol, tacrolimus, ziprasidone, or other drugs that have demonstrated QT prolongation as one of their pharmacodynamic effects.

Source: FDA drug label (Pimozide), Par Health USA, LLC, effective August 12, 2026 (SPL set 70b079e2-a1f7-4a93-8685-d60a4d7c1280), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

2Droperidol generic labelers
2Pimozide generic labelers
DroperidolPimozide
Labeled forn/an/a
Boxed warningYesNo
Pharmacy cost (NADAC)n/a$1.23 per tablet 1 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?