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What the FDA labels say about taking them together

Dronabinol and scopolamine

Dronabinol's FDA label of May 6, 2026 names scopolamine in its warnings and precautions section; the scopolamine label PlainMeds reads does not name dronabinol. The dronabinol label: “Concomitant use of other drugs that cause dizziness, confusion, sedation, or somnolence such as CNS depressants may increase this effect.”

Check it at the source: the dronabinol FDA label on DailyMed (effective May 6, 2026, Ascend Laboratories, LLC); the scopolamine FDA label on DailyMed (effective June 10, 2025, Baxter Healthcare Corporation).

What does the dronabinol label say about scopolamine?

Dronabinol label, warnings and precautions

Concomitant use of other drugs that cause dizziness, confusion, sedation, or somnolence such as CNS depressants may increase this effect (e.g., barbiturates, benzodiazepines, ethanol, lithium, opioids, buspirone, scopolamine, antihistamines, tricyclic antidepressants, other anticholinergic agents, muscle relaxants).

Source: FDA drug label (Syndros, NDA205525), Wellhouse Pharma, LLC, effective April 17, 2026 (SPL set 3cdcb4f5-5af9-4ff7-b535-2a5cf4c6da89), via openFDA

Source: FDA drug label (Dronabinol), NDA018651 (Alkem Labs Ltd), as published by Ascend Laboratories, LLC, effective May 6, 2026 (SPL set adb1801c-0fb5-4e16-b969-1db91230e0b9), via openFDA; the full label on DailyMed

What does the scopolamine label say about dronabinol?

Scopolamine's label (effective June 10, 2025) does not name dronabinol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Transderm Scop), Baxter Healthcare Corporation, effective June 10, 2025 (SPL set b877a694-a1d0-4280-937a-a06820b12a88), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Dronabinol generic labelers
11Scopolamine generic labelers
DronabinolScopolamine
Labeled forn/aNausea and vomiting
Boxed warningNoNo
Pharmacy cost (NADAC)$3.35 per capsule 5 mg capsule$4.34 per patch 1 mg/3 day patch
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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