What the FDA labels say about taking them together
Dronabinol and ritonavir
Dronabinol's FDA label of May 6, 2026 names ritonavir in its drug interactions section, and ritonavir's label names dronabinol too. The ritonavir label: “A dose decrease of dronabinol may be needed when co-administered with ritonavir.”
Check it at the source: the dronabinol FDA label on DailyMed (effective May 6, 2026, Ascend Laboratories, LLC); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the dronabinol label say about ritonavir?
Dronabinol label, drug interactionsMonitor for potentially increased dronabinol-related adverse reactions when dronabinol capsules are co-administered with inhibitors of CYP2C9 (e.g., amiodarone, fluconazole) and inhibitors of CYP3A4 enzymes (e.g., ketoconazole, itraconazole, clarithromycin, ritonavir, erythromycin, grapefruit juice).
Source: FDA drug label (Syndros, NDA205525), Wellhouse Pharma, LLC, effective April 17, 2026 (SPL set 3cdcb4f5-5af9-4ff7-b535-2a5cf4c6da89), via openFDA
Source: FDA drug label (Dronabinol), NDA018651 (Alkem Labs Ltd), as published by Ascend Laboratories, LLC, effective May 6, 2026 (SPL set adb1801c-0fb5-4e16-b969-1db91230e0b9), via openFDA; the full label on DailyMed
What does the ritonavir label say about dronabinol?
Ritonavir label, drug interactionsConcomitant Drug Class/Drug Name: Antiemetic: dronabinol; Effect on Concentration of Ritonavir or Concomitant Drug: ↑ dronabinol; Clinical Comment: A dose decrease of dronabinol may be needed when co-administered with ritonavir.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dronabinol | Ritonavir | |
|---|---|---|
| Labeled for | n/a | HIV |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $3.35 per capsule 5 mg capsule | $0.607 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once