What the FDA labels say about taking them together
Dronabinol and lithium
Dronabinol's FDA label of May 6, 2026 names lithium in its warnings and precautions section; the lithium labels PlainMeds reads (4) do not name dronabinol. The dronabinol label: “Concomitant use of other drugs that cause dizziness, confusion, sedation, or somnolence such as CNS depressants may increase this effect.”
Check it at the source: the dronabinol FDA label on DailyMed (effective May 6, 2026, Ascend Laboratories, LLC); the lithium FDA label on DailyMed (effective December 23, 2025, Glenmark Pharmaceuticals Inc., USA).
What does the dronabinol label say about lithium?
Dronabinol label, warnings and precautionsConcomitant use of other drugs that cause dizziness, confusion, sedation, or somnolence such as CNS depressants may increase this effect (e.g., barbiturates, benzodiazepines, ethanol, lithium, opioids, buspirone, scopolamine, antihistamines, tricyclic antidepressants, other anticholinergic agents, muscle relaxants).
Source: FDA drug label (Syndros, NDA205525), Wellhouse Pharma, LLC, effective April 17, 2026 (SPL set 3cdcb4f5-5af9-4ff7-b535-2a5cf4c6da89), via openFDA
Source: FDA drug label (Dronabinol), NDA018651 (Alkem Labs Ltd), as published by Ascend Laboratories, LLC, effective May 6, 2026 (SPL set adb1801c-0fb5-4e16-b969-1db91230e0b9), via openFDA; the full label on DailyMed
What does the lithium label say about dronabinol?
Lithium's label (effective December 23, 2025) and its 3 other brand-application labels do not name dronabinol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lithium Carbonate), Glenmark Pharmaceuticals Inc., USA, effective December 23, 2025 (SPL set 63b3790f-a9b5-47f4-bae1-ddf8b43c13c1), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dronabinol | Lithium | |
|---|---|---|
| Labeled for | n/a | Bipolar disorder |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $3.35 per capsule 5 mg capsule | $0.104 per capsule 300 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once