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What the FDA labels say about taking them together

Doxorubicin and valganciclovir

Valganciclovir's FDA label of December 8, 2025 names doxorubicin in its drug interactions section; the doxorubicin labels PlainMeds reads (2) do not name valganciclovir. The valganciclovir label: “Because of potential for higher toxicity, coadministration with VALCYTE should be considered only if the potential benefits are judged to outweigh the risks.”

Check it at the source: the doxorubicin FDA label on DailyMed (effective May 5, 2026, Pfizer Laboratories Div Pfizer Inc); the valganciclovir FDA label on DailyMed (effective December 8, 2025, H2-Pharma, LLC).

What does the doxorubicin label say about valganciclovir?

Doxorubicin's label (effective May 5, 2026) and its 1 other brand-application label do not name valganciclovir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Doxorubicin Hydrochloride), Pfizer Laboratories Div Pfizer Inc, effective May 5, 2026 (SPL set 1fd148fb-0fbc-4b6f-b790-23546fb46a71), via openFDA; the full label on DailyMed

What does the valganciclovir label say about doxorubicin?

Valganciclovir label, drug interactions

Name of the Concomitant Drug: Other drugs associated with myelosuppression or nephrotoxicity (e.g., adriamycin, dapsone, doxorubicin, flucytosine, hydroxyurea, pentamidine, tacrolimus, trimethoprim/ sulfamethoxazole, vinblastine, vincristine, and zidovudine); Change in the Concentration of Ganciclovir or Concomitant Drug: Unknown; Clinical Comment: Because of potential for higher toxicity, coadministration with VALCYTE should be considered only if the potential benefits are judged to outweigh the risks.

Source: FDA drug label (Valcyte), NDA021304 (Cheplapharm), as published by H2-Pharma, LLC, effective December 8, 2025 (SPL set 4c517a39-2ded-4c5a-8d56-276853414b31), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

16Doxorubicin generic labelers
19Valganciclovir generic labelers
DoxorubicinValganciclovir
Labeled forLeukemia, lymphoma and myeloma, Breast cancern/a
Boxed warningYesYes
Pharmacy cost (NADAC)n/a$1.91 per tablet 450 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?