What the FDA labels say about taking them together
Doxapram and theophylline
Doxapram's FDA label of April 9, 2024 names theophylline in its drug interactions section; the theophylline label PlainMeds reads does not name doxapram. The doxapram label: “There may be an interaction between doxapram and aminophylline and between doxapram and theophylline manifested by increased skeletal muscle activity, agitation, and hyperactivity.”
Check it at the source: the doxapram FDA label on DailyMed (effective April 9, 2024, Hikma Pharmaceuticals USA Inc.); the theophylline FDA label on DailyMed (effective March 10, 2026, Strides Pharma Science Limited).
What does the doxapram label say about theophylline?
Doxapram label, drug interactionsThere may be an interaction between doxapram and aminophylline and between doxapram and theophylline manifested by increased skeletal muscle activity, agitation, and hyperactivity.
Source: FDA drug label (Dopram), Hikma Pharmaceuticals USA Inc., effective April 9, 2024 (SPL set b8eb330a-a75b-46cb-b694-5be9327ed2eb), via openFDA; the full label on DailyMed
What does the theophylline label say about doxapram?
Theophylline's label (effective March 10, 2026) does not name doxapram in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Theophylline), Strides Pharma Science Limited, effective March 10, 2026 (SPL set b7a90ccf-9c32-40cc-9008-7e55b3da4dfd), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Doxapram | Theophylline | |
|---|---|---|
| Labeled for | n/a | Asthma |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.330 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once