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What the FDA labels say about taking them together

Dopamine and selegiline

Dopamine's FDA label of May 12, 2026 names selegiline in its drug interactions section; the selegiline labels PlainMeds reads (3) do not name dopamine.

Check it at the source: the dopamine FDA label on DailyMed (effective May 12, 2026, Hospira, Inc.); the selegiline FDA label on DailyMed (effective August 7, 2024, Rising Pharma Holdings, Inc.).

What does the dopamine label say about selegiline?

Dopamine label, drug interactions

MAO Inhibitors Clinical Impact: Because dopamine is metabolized by monoamine oxidase (MAO), inhibition of this enzyme prolongs and potentiates the effect of dopamine which may result in severe hypertension and cardiac arrhythmia. … of Dopamine HCl in Dextrose Injection. Examples: isocarboxazid, phenelzine, tranylcypromine, rasagiline, selegiline, linezolid.

Source: FDA drug label (Dopamine Hydrochloride in Dextrose), Hospira, Inc., effective May 12, 2026 (SPL set 08f23f6e-150d-45ea-098e-f2edf64c21a1), via openFDA; the full label on DailyMed

What does the selegiline label say about dopamine?

Selegiline's label (effective August 7, 2024) and its 2 other brand-application labels do not name dopamine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Selegiline Hydrochloride), Rising Pharma Holdings, Inc., effective August 7, 2024 (SPL set 23c4481f-d150-40c6-addb-b3e454ca914f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Dopamine generic labelers
11Selegiline generic labelers
DopamineSelegiline
Labeled forn/aParkinson's disease, Depression
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.756 per capsule 5 mg capsule
Shortage nowIn shortageNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?