What the FDA labels say about taking them together
Docetaxel and epirubicin
Epirubicin's FDA label of July 24, 2026 names docetaxel in its drug interactions section; the docetaxel labels PlainMeds reads (4) do not name epirubicin. The epirubicin label: “The administration of epirubicin immediately prior to or after docetaxel did not have an effect on the systemic exposure of epirubicin, but increased the systemic exposure of epirubicinol and 7-deoxydoxorubicin aglycone.”
Check it at the source: the docetaxel FDA label on DailyMed (effective July 15, 2025, Avyxa Pharma, LLC); the epirubicin FDA label on DailyMed (effective July 24, 2026, Pharmacia & Upjohn Company LLC).
What does the docetaxel label say about epirubicin?
Docetaxel's label (effective July 15, 2025) and its 3 other brand-application labels do not name epirubicin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (DOCIVYX), Avyxa Pharma, LLC, effective July 15, 2025 (SPL set 4763744e-360e-4d37-be05-cce4114548cd), via openFDA; the full label on DailyMed
What does the epirubicin label say about docetaxel?
Epirubicin label, drug interactionsThe administration of epirubicin immediately prior to or after docetaxel did not have an effect on the systemic exposure of epirubicin, but increased the systemic exposure of epirubicinol and 7-deoxydoxorubicin aglycone [see Clinical Pharmacology (12.3) ].
Source: FDA drug label (Ellence), NDA050778 (Pfizer Inc), as published by Pharmacia & Upjohn Company LLC, effective July 24, 2026 (SPL set 0a03c798-a652-4895-b29c-3b521a89ba42), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Docetaxel | Epirubicin | |
|---|---|---|
| Labeled for | Breast cancer, Lung cancer, Prostate cancer | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once