What the FDA labels say about taking them together
Disulfiram and thalidomide
Thalidomide's FDA label of March 24, 2023 names disulfiram in its drug interactions section; the disulfiram label PlainMeds reads does not name thalidomide.
Check it at the source: the disulfiram FDA label on DailyMed (effective August 20, 2024, Sigmapharm Laboratories, LLC); the thalidomide FDA label on DailyMed (effective March 24, 2023, Celgene Corporation).
What does the disulfiram label say about thalidomide?
Disulfiram's label (effective August 20, 2024) does not name thalidomide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Disulfiram), Sigmapharm Laboratories, LLC, effective August 20, 2024 (SPL set 40f5497f-fe84-43b2-8ff4-32d59edf3917), via openFDA; the full label on DailyMed
What does the thalidomide label say about disulfiram?
Thalidomide label, drug interactionsDrugs which Cause Peripheral Neuropathy The use of drugs which cause peripheral neuropathy (e.g., bortezomib, amiodarone, cisplatin, docetaxel, paclitaxel, vincristine, disulfiram, phenytoin, metronidazole, alcohol) can cause an additive effect and should be used with caution.
Source: FDA drug label (Thalomid), NDA020785 (Bristol-Myers), as published by Celgene Corporation, effective March 24, 2023 (SPL set 2eda833b-1357-4ed4-a093-194524fcb061), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Disulfiram | Thalidomide | |
|---|---|---|
| Labeled for | Alcohol use disorder | Leukemia, lymphoma and myeloma |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $1.82 per tablet 250 mg tablet | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once