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What the FDA labels say about taking them together

Disulfiram and procarbazine

Procarbazine's FDA label of September 16, 2024 names disulfiram in its warnings section; the disulfiram label PlainMeds reads does not name procarbazine.

Check it at the source: the disulfiram FDA label on DailyMed (effective August 20, 2024, Sigmapharm Laboratories, LLC); the procarbazine FDA label on DailyMed (effective September 16, 2024, Leadiant Biosciences, Inc.).

What does the disulfiram label say about procarbazine?

Disulfiram's label (effective August 20, 2024) does not name procarbazine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Disulfiram), Sigmapharm Laboratories, LLC, effective August 20, 2024 (SPL set 40f5497f-fe84-43b2-8ff4-32d59edf3917), via openFDA; the full label on DailyMed

What does the procarbazine label say about disulfiram?

Procarbazine label, warnings

Ethyl alcohol should not be used since there may be an Antabuse (disulfiram)-like reaction.

Source: FDA drug label (Matulane), Leadiant Biosciences, Inc., effective September 16, 2024 (SPL set 1aa75a3a-18c9-49e1-91a6-293d0b7da756), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

5Disulfiram generic labelers
0Procarbazine generic labelers
DisulfiramProcarbazine
Labeled forAlcohol use disordern/a
Boxed warningYesYes
Pharmacy cost (NADAC)$1.82 per tablet 250 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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