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What the FDA labels say about taking them together

Disulfiram and isocarboxazid

Isocarboxazid's FDA label of April 21, 2026 names disulfiram in its drug interactions section; the disulfiram label PlainMeds reads does not name isocarboxazid.

Check it at the source: the disulfiram FDA label on DailyMed (effective August 20, 2024, Sigmapharm Laboratories, LLC); the isocarboxazid FDA label on DailyMed (effective April 21, 2026, Lifsa Drugs LLC).

What does the disulfiram label say about isocarboxazid?

Disulfiram's label (effective August 20, 2024) does not name isocarboxazid in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Disulfiram), Sigmapharm Laboratories, LLC, effective August 20, 2024 (SPL set 40f5497f-fe84-43b2-8ff4-32d59edf3917), via openFDA; the full label on DailyMed

What does the isocarboxazid label say about disulfiram?

Isocarboxazid label, drug interactions

Marplan should be administered with caution to patients receiving Antabuse ® (disulfiram, Wyeth-Ayerst Laboratories).

Source: FDA drug label (MARPLAN), Lifsa Drugs LLC, effective April 21, 2026 (SPL set 95fde749-44ad-4668-86c4-0ff17bca0074), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

5Disulfiram generic labelers
0Isocarboxazid generic labelers
DisulfiramIsocarboxazid
Labeled forAlcohol use disorderDepression
Boxed warningYesYes
Pharmacy cost (NADAC)$1.82 per tablet 250 mg tabletn/a
Shortage nowNo current entryIn shortage

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?