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What the FDA labels say about taking them together

Disopyramide and toremifene

Toremifene's FDA label of November 13, 2024 names disopyramide in its drug interactions section; the disopyramide label PlainMeds reads does not name toremifene. The toremifene label: “Agents generally accepted to prolong QT interval include Class 1A and Class III antiarrhythmics; certain antipsychotics; certain antidepressants; certain antibiotics; and certain anti-emetics.”

Check it at the source: the disopyramide FDA label on DailyMed (effective August 24, 2026, Pfizer Laboratories Div Pfizer Inc); the toremifene FDA label on DailyMed (effective November 13, 2024, Kyowa Kirin, Inc.).

What does the disopyramide label say about toremifene?

Disopyramide's label (effective August 24, 2026) does not name toremifene in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Norpace), Pfizer Laboratories Div Pfizer Inc, effective August 24, 2026 (SPL set e2aa1642-d262-4520-bc6a-9fd3ad795677), via openFDA; the full label on DailyMed

What does the toremifene label say about disopyramide?

Toremifene label, drug interactions

Agents generally accepted to prolong QT interval include Class 1A (e.g., quinidine, procainamide, disopyramide) and Class III (e.g., amiodarone, sotalol, ibutilide, dofetilide) antiarrhythmics; certain antipsychotics (e.g., thioridazine, haloperidol); certain antidepressants (e.g., venlafaxine, amitriptyline); certain antibiotics (e.g., erythromycin, clarithromycin, levofloxacin, ofloxacin); and certain anti-emetics (e.g., ondansetron, granisetron).

Source: FDA drug label (Fareston), Kyowa Kirin, Inc., effective November 13, 2024 (SPL set 2cab8dd1-3a10-48e6-86ce-0e5275ed49e5), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

2Disopyramide generic labelers
2Toremifene generic labelers
DisopyramideToremifene
Labeled forn/aBreast cancer
Boxed warningYesYes
Pharmacy cost (NADAC)$0.801 per capsule 100 mg capsule$19.60 per tablet 60 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?