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What the FDA labels say about taking them together

Disopyramide and nebivolol

Nebivolol's FDA label of August 1, 2024 names disopyramide in its drug interactions section; the disopyramide label PlainMeds reads does not name nebivolol.

Check it at the source: the disopyramide FDA label on DailyMed (effective August 24, 2026, Pfizer Laboratories Div Pfizer Inc); the nebivolol FDA label on DailyMed (effective August 1, 2024, Allergan, Inc.).

What does the disopyramide label say about nebivolol?

Disopyramide's label (effective August 24, 2026) does not name nebivolol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Norpace), Pfizer Laboratories Div Pfizer Inc, effective August 24, 2026 (SPL set e2aa1642-d262-4520-bc6a-9fd3ad795677), via openFDA; the full label on DailyMed

What does the nebivolol label say about disopyramide?

Nebivolol label, drug interactions

Calcium Channel Blockers BYSTOLIC can exacerbate the effects of myocardial depressants or inhibitors of AV conduction, such as certain calcium antagonists (particularly of the phenylalkylamine [verapamil] and benzothiazepine [diltiazem] classes), or antiarrhythmic agents, such as disopyramide.

Source: FDA drug label (Bystolic), Allergan, Inc., effective August 1, 2024 (SPL set 8b8ad213-1dc8-454e-a524-075685c0e1a8), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

2Disopyramide generic labelers
23Nebivolol generic labelers
DisopyramideNebivolol
Labeled forn/aHigh blood pressure
Boxed warningYesNo
Pharmacy cost (NADAC)$0.801 per capsule 100 mg capsule$0.141 per tablet 10 mg tablet
Shortage nowA presentation being discontinuedA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?