What the FDA labels say about taking them together
Disopyramide and lidocaine
Disopyramide's FDA label of August 24, 2026 names lidocaine in its drug interactions section; the lidocaine labels PlainMeds reads (4) do not name disopyramide.
Check it at the source: the disopyramide FDA label on DailyMed (effective August 24, 2026, Pfizer Laboratories Div Pfizer Inc); the lidocaine FDA label on DailyMed (effective May 13, 2024, Fresenius Kabi USA, LLC).
What does the disopyramide label say about lidocaine?
Disopyramide label, drug interactionsOther antiarrhythmic drugs (e.g., quinidine, procainamide, lidocaine, propranolol) have occasionally been used concurrently with Norpace.
Source: FDA drug label (Norpace), Pfizer Laboratories Div Pfizer Inc, effective August 24, 2026 (SPL set e2aa1642-d262-4520-bc6a-9fd3ad795677), via openFDA; the full label on DailyMed
What does the lidocaine label say about disopyramide?
Lidocaine's label (effective May 13, 2024) and its 3 other brand-application labels do not name disopyramide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Xylocaine MPF), Fresenius Kabi USA, LLC, effective May 13, 2024 (SPL set d5e0d06f-ba1e-44d4-aa89-39d6c146dc23), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Disopyramide | Lidocaine | |
|---|---|---|
| Labeled for | n/a | Pain |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.801 per capsule 100 mg capsule | $0.154 per gram 5% ointment |
| Shortage now | A presentation being discontinued | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once