What the FDA labels say about taking them together
Disopyramide and glipizide
Glipizide's FDA label of January 8, 2026 names disopyramide in its drug interactions section; the disopyramide label PlainMeds reads does not name glipizide. The glipizide label: “… antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin …”
Check it at the source: the disopyramide FDA label on DailyMed (effective August 24, 2026, Pfizer Laboratories Div Pfizer Inc); the glipizide FDA label on DailyMed (effective January 8, 2026, Aurobindo Pharma Limited).
What does the disopyramide label say about glipizide?
Disopyramide's label (effective August 24, 2026) does not name glipizide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Norpace), Pfizer Laboratories Div Pfizer Inc, effective August 24, 2026 (SPL set e2aa1642-d262-4520-bc6a-9fd3ad795677), via openFDA; the full label on DailyMed
What does the glipizide label say about disopyramide?
Glipizide label, drug interactionsThe following are examples of medication that may increase the glucose lowering effect of glipizide extended-release tablets, increase the susceptibility to and/or intensity of hypoglycemia: antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, propoxyphene, salicylates, somatostatin analogs (e.g., octreotide), sulfonamide antibiotics, nonsteroidal anti-inflammatory agents, chloramphenicol, probenecid, coumarins, voriconazole, H2 receptor antagonists, and quinolones.
Source: FDA drug label (Glucotrol Xl, NDA020329), Roerig, effective July 21, 2026 (SPL set eed99b60-d043-4249-9b2a-f05e46fb588d), via openFDA
Source: FDA drug label (Glipizide), Aurobindo Pharma Limited, effective January 8, 2026 (SPL set 84794a52-b717-488c-8533-6425c83d405f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Disopyramide | Glipizide | |
|---|---|---|
| Labeled for | n/a | Type 2 diabetes |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.801 per capsule 100 mg capsule | $0.0339 per tablet 5 mg tablet |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once