Skip to main content

What the FDA labels say about taking them together

Dimethyl sulfoxide and verteporfin

Verteporfin's FDA label of August 27, 2025 names dimethyl sulfoxide in its drug interactions section; the dimethyl sulfoxide label PlainMeds reads does not name verteporfin. The verteporfin label: “Compounds that quench active oxygen species or scavenge radicals, such as dimethyl sulfoxide, β-carotene, ethanol, formate and mannitol, would be expected to decrease VISUDYNE activity.”

Check it at the source: the dimethyl sulfoxide FDA label on DailyMed (effective March 17, 2021, Mylan Institutional LLC); the verteporfin FDA label on DailyMed (effective August 27, 2025, Bausch Health US LLC).

What does the dimethyl sulfoxide label say about verteporfin?

Dimethyl sulfoxide's label (effective March 17, 2021) does not name verteporfin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (RIMSO-50), Mylan Institutional LLC, effective March 17, 2021 (SPL set 58b25d79-78f2-4953-b0c6-61658dc4ef0d), via openFDA; the full label on DailyMed

What does the verteporfin label say about dimethyl sulfoxide?

Verteporfin label, drug interactions

Compounds that quench active oxygen species or scavenge radicals, such as dimethyl sulfoxide, β-carotene, ethanol, formate and mannitol, would be expected to decrease VISUDYNE activity.

Source: FDA drug label (Visudyne), Bausch Health US LLC, effective August 27, 2025 (SPL set 952f4c80-50b1-4308-9ee6-311ffefb13df), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Dimethyl sulfoxide generic labelers
0Verteporfin generic labelers
Dimethyl sulfoxideVerteporfin
Labeled forn/an/a
Boxed warningNoNo
Pharmacy cost (NADAC)n/an/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?