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What the FDA labels say about taking them together

Dimethyl sulfoxide and remestemcel-l-rknd

Remestemcel-l-rknd's FDA label of September 11, 2025 names dimethyl sulfoxide in its contraindications section; the dimethyl sulfoxide label PlainMeds reads does not name remestemcel-l-rknd. The remestemcel-l-rknd label: “CONTRAINDICATIONS Do not use RYONCIL in patients with known hypersensitivity to dimethyl sulfoxide (DMSO) or porcine and bovine proteins.”

Check it at the source: the dimethyl sulfoxide FDA label on DailyMed (effective March 17, 2021, Mylan Institutional LLC); the remestemcel-l-rknd FDA label on DailyMed (effective September 11, 2025).

What does the dimethyl sulfoxide label say about remestemcel-l-rknd?

Dimethyl sulfoxide's label (effective March 17, 2021) does not name remestemcel-l-rknd in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (RIMSO-50), Mylan Institutional LLC, effective March 17, 2021 (SPL set 58b25d79-78f2-4953-b0c6-61658dc4ef0d), via openFDA; the full label on DailyMed

What does the remestemcel-l-rknd label say about dimethyl sulfoxide?

Remestemcel-l-rknd label, contraindications

CONTRAINDICATIONS Do not use RYONCIL in patients with known hypersensitivity to dimethyl sulfoxide (DMSO) or porcine and bovine proteins.

Source: FDA drug label (RYONCIL), Mesoblast, effective September 11, 2025 (SPL set a4e0918f-7444-4694-adeb-d38d98345659), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

1Dimethyl sulfoxide generic labelers
0Remestemcel-l-rknd generic labelers
Dimethyl sulfoxideRemestemcel-l-rknd
Labeled forn/an/a
Boxed warningNoNo
Pharmacy cost (NADAC)n/an/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?