What the FDA labels say about taking them together
Dienogest/estradiol and griseofulvin
Dienogest/estradiol's FDA label of June 26, 2024 names griseofulvin in its drug interactions section; the griseofulvin label PlainMeds reads does not name dienogest/estradiol. The dienogest/estradiol label: “Some drugs or herbal products that may decrease the effectiveness of hormonal contraceptives include phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampin, topiramate and …”
Check it at the source: the dienogest/estradiol FDA label on DailyMed (effective June 26, 2024, Bayer HealthCare Pharmaceuticals Inc.); the griseofulvin FDA label on DailyMed (effective December 10, 2025).
What does the dienogest/estradiol label say about griseofulvin?
Dienogest/estradiol label, drug interactionsSome drugs or herbal products that may decrease the effectiveness of hormonal contraceptives include phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampin, topiramate and products containing St. John’s wort.
Source: FDA drug label (Natazia), Bayer HealthCare Pharmaceuticals Inc., effective June 26, 2024 (SPL set 02c91fba-9c47-43ef-ac78-e82369798834), via openFDA; the full label on DailyMed
What does the griseofulvin label say about dienogest/estradiol?
Griseofulvin's label (effective December 10, 2025) does not name dienogest/estradiol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Ultramicrosize Griseofulvin), Chartwell RX, LLC., effective December 10, 2025 (SPL set efb8a660-802c-4ca6-bbff-ad7b48b91aef), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dienogest/estradiol | Griseofulvin | |
|---|---|---|
| Labeled for | Birth control | Fungal infections |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $8.46 per tablet 28 tablet | $3.74 per tablet 250 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once