What the FDA labels say about taking them together
Dichlorphenamide and famotidine
Dichlorphenamide's FDA label of March 4, 2026 names famotidine in its drug interactions section; the famotidine labels PlainMeds reads (2) do not name dichlorphenamide. The dichlorphenamide label: “Use of KEVEYIS with drugs that are sensitive to OAT1 inhibition is not recommended.”
Check it at the source: the dichlorphenamide FDA label on DailyMed (effective March 4, 2026, Xeris Pharmaceuticals, Inc.); the famotidine FDA label on DailyMed (effective February 6, 2026, Kenvue Brands LLC).
What does the dichlorphenamide label say about famotidine?
Dichlorphenamide label, drug interactionsUse of KEVEYIS with drugs that are sensitive to OAT1 inhibition (e.g., methotrexate, famotidine, oseltamivir) is not recommended [see Clinical Pharmacology (12.3) ].
Source: FDA drug label (Keveyis), Xeris Pharmaceuticals, Inc., effective March 4, 2026 (SPL set d30a87b9-90fb-35b2-e053-2995a90aea2c), via openFDA; the full label on DailyMed
What does the famotidine label say about dichlorphenamide?
Famotidine's label (effective February 6, 2026) and its 1 other brand-application label do not name dichlorphenamide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Pepcid AC Original Strength), Kenvue Brands LLC, effective February 6, 2026 (SPL set 54f4086f-e443-4e7e-8c7e-94e152e1c256), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dichlorphenamide | Famotidine | |
|---|---|---|
| Labeled for | n/a | Acid reflux and ulcers |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | $0.0289 per tablet 20 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once