What the FDA labels say about taking them together
Diazepam and ritonavir
Ritonavir's FDA label of July 23, 2026 names diazepam in its drug interactions section; the diazepam labels PlainMeds reads (4) do not name ritonavir. The ritonavir label: “A dose decrease may be needed for these drugs when co-administered with ritonavir.”
Check it at the source: the diazepam FDA label on DailyMed (effective August 11, 2026, Waylis Therapuetics LLC); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the diazepam label say about ritonavir?
Diazepam's label (effective August 11, 2026) and its 3 other brand-application labels do not name ritonavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Valium), Waylis Therapuetics LLC, effective August 11, 2026 (SPL set 260e2041-2bb3-482f-850e-b5d47a7bdbe6), via openFDA; the full label on DailyMed
What does the ritonavir label say about diazepam?
Ritonavir label, drug interactionsConcomitant Drug Class/Drug Name: Sedative/hypnotics: buspirone, clorazepate, diazepam, estazolam, flurazepam, zolpidem; Effect on Concentration of Ritonavir or Concomitant Drug: ↑ sedative/hypnotics; Clinical Comment: A dose decrease may be needed for these drugs when co-administered with ritonavir.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Diazepam | Ritonavir | |
|---|---|---|
| Labeled for | Anxiety, Muscle spasms and spasticity | HIV |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.0283 per tablet 10 mg tablet | $0.607 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once