What the FDA labels say about taking them together
Diazepam and etravirine
Etravirine's FDA label of August 15, 2023 names diazepam in its drug interactions section; the diazepam labels PlainMeds reads (4) do not name etravirine. The etravirine label: “Concomitant use of INTELENCE with diazepam may increase plasma concentrations of diazepam. A decrease in diazepam dose may be needed.”
Check it at the source: the diazepam FDA label on DailyMed (effective August 11, 2026, Waylis Therapuetics LLC); the etravirine FDA label on DailyMed (effective August 15, 2023, Janssen Products LP).
What does the diazepam label say about etravirine?
Diazepam's label (effective August 11, 2026) and its 3 other brand-application labels do not name etravirine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Valium), Waylis Therapuetics LLC, effective August 11, 2026 (SPL set 260e2041-2bb3-482f-850e-b5d47a7bdbe6), via openFDA; the full label on DailyMed
What does the etravirine label say about diazepam?
Etravirine label, drug interactionsConcomitant Drug Class/Drug Name: Benzodiazepine: diazepam; Effect on Concentration of Etravirine or Concomitant Drug: ↑ diazepam; Clinical Comment: Concomitant use of INTELENCE with diazepam may increase plasma concentrations of diazepam. A decrease in diazepam dose may be needed.
Source: FDA drug label (Intelence), Janssen Products LP, effective August 15, 2023 (SPL set 6a9cbc29-9f15-4b24-8d86-206b82887f3d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Diazepam | Etravirine | |
|---|---|---|
| Labeled for | Anxiety, Muscle spasms and spasticity | HIV |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.0283 per tablet 10 mg tablet | $9.94 per tablet 200 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once