What the FDA labels say about taking them together
Dexamethasone and gilteritinib
Gilteritinib's FDA label of January 1, 2022 names dexamethasone in its warnings and precautions section; the dexamethasone labels PlainMeds reads (4) do not name gilteritinib. The gilteritinib label: “If differentiation syndrome is suspected, initiate dexamethasone 10 mg IV every 12 hours and hemodynamic monitoring until improvement.”
Check it at the source: the dexamethasone FDA label on DailyMed (effective June 6, 2025, Hikma Pharmaceuticals USA, Inc.); the gilteritinib FDA label on DailyMed (effective January 1, 2022, Astellas Pharma US, Inc.).
What does the dexamethasone label say about gilteritinib?
Dexamethasone's label (effective June 6, 2025) and its 3 other brand-application labels do not name gilteritinib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Dexamethasone Intensol), Hikma Pharmaceuticals USA, Inc., effective June 6, 2025 (SPL set b15200fb-1826-472b-a907-e677a272513b), via openFDA; the full label on DailyMed
What does the gilteritinib label say about dexamethasone?
Gilteritinib label, warnings and precautionsIf differentiation syndrome is suspected, initiate dexamethasone 10 mg IV every 12 hours (or an equivalent dose of an alternative oral or IV corticosteroid) and hemodynamic monitoring until improvement.
Source: FDA drug label (Xospata), Astellas Pharma US, Inc., effective January 1, 2022 (SPL set b5ff59aa-9c0d-49a8-9053-1f179b482383), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dexamethasone | Gilteritinib | |
|---|---|---|
| Labeled for | Asthma, Eczema (atopic dermatitis), Leukemia, lymphoma and myeloma, Herpes and shingles, Crohn's disease and ulcerative colitis, Multiple sclerosis, Osteoarthritis, Rheumatoid arthritis, Psoriasis, Allergies, Anemia, Pain | n/a |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.193 per tablet 4 mg tablet | n/a |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once