What the FDA labels say about taking them together
Dexamethasone and enasidenib
Enasidenib's FDA label of January 16, 2025 names dexamethasone in its warnings and precautions section; the dexamethasone labels PlainMeds reads (4) do not name enasidenib. The enasidenib label: “If differentiation syndrome is suspected, initiate oral or intravenous corticosteroids and hemodynamic monitoring until improvement.”
Check it at the source: the dexamethasone FDA label on DailyMed (effective June 6, 2025, Hikma Pharmaceuticals USA, Inc.); the enasidenib FDA label on DailyMed (effective January 16, 2025, Celgene Corporation).
What does the dexamethasone label say about enasidenib?
Dexamethasone's label (effective June 6, 2025) and its 3 other brand-application labels do not name enasidenib in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Dexamethasone Intensol), Hikma Pharmaceuticals USA, Inc., effective June 6, 2025 (SPL set b15200fb-1826-472b-a907-e677a272513b), via openFDA; the full label on DailyMed
What does the enasidenib label say about dexamethasone?
Enasidenib label, warnings and precautionsIf differentiation syndrome is suspected, initiate oral or intravenous corticosteroids (e.g., dexamethasone 10 mg every 12 hours) and hemodynamic monitoring until improvement.
Source: FDA drug label (Idhifa), NDA209606 (Bristol Myers Squibb), as published by Celgene Corporation, effective January 16, 2025 (SPL set a5b4cdf0-3fa8-4c6c-80f6-8d8a00e3a5b6), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dexamethasone | Enasidenib | |
|---|---|---|
| Labeled for | Asthma, Eczema (atopic dermatitis), Leukemia, lymphoma and myeloma, Herpes and shingles, Crohn's disease and ulcerative colitis, Multiple sclerosis, Osteoarthritis, Rheumatoid arthritis, Psoriasis, Allergies, Anemia, Pain | Leukemia, lymphoma and myeloma |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.193 per tablet 4 mg tablet | n/a |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once