What the FDA labels say about taking them together
Cholestyramine and dexamethasone
Dexamethasone's FDA label of June 6, 2025 names cholestyramine in its drug interactions section; the cholestyramine label PlainMeds reads does not name dexamethasone. The dexamethasone label: “Cholestyramine: Cholestyramine may increase the clearance of corticosteroids.”
Check it at the source: the cholestyramine FDA label on DailyMed (effective August 20, 2026, AiPing Pharmaceutical, Inc.); the dexamethasone FDA label on DailyMed (effective June 6, 2025, Hikma Pharmaceuticals USA, Inc.).
What does the cholestyramine label say about dexamethasone?
Cholestyramine's label (effective August 20, 2026) does not name dexamethasone in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cholestyramine), AiPing Pharmaceutical, Inc., effective August 20, 2026 (SPL set 214ea05f-de81-4026-9df9-4ce3820668ee), via openFDA; the full label on DailyMed
What does the dexamethasone label say about cholestyramine?
Dexamethasone label, drug interactionsCholestyramine: Cholestyramine may increase the clearance of corticosteroids.
Hemady label (Edenbridge Pharmaceuticals LLC., January 9, 2026), drug interactionsCholestyramine Cholestyramine may increase the clearance of corticosteroids and potentially decrease corticosteroid exposure.
Source: FDA drug label (Hemady, NDA211379), Edenbridge Pharmaceuticals LLC., effective January 9, 2026 (SPL set 6b9cf32c-6d60-4853-bbfd-2304ffc2c129), via openFDA
Source: FDA drug label (Dexamethasone Intensol), Hikma Pharmaceuticals USA, Inc., effective June 6, 2025 (SPL set b15200fb-1826-472b-a907-e677a272513b), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cholestyramine | Dexamethasone | |
|---|---|---|
| Labeled for | High cholesterol | Asthma, Eczema (atopic dermatitis), Leukemia, lymphoma and myeloma, Herpes and shingles, Crohn's disease and ulcerative colitis, Multiple sclerosis, Osteoarthritis, Rheumatoid arthritis, Psoriasis, Allergies, Anemia, Pain |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.834 per packet Cholestyramine packet | $0.193 per tablet 4 mg tablet |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once