What the FDA labels say about taking them together
Deutetrabenazine and valbenazine
Deutetrabenazine's FDA label of February 28, 2025 names valbenazine in its contraindications section; the valbenazine label PlainMeds reads does not name deutetrabenazine. The deutetrabenazine label: “Tetrabenazine or Valbenazine AUSTEDO XR and AUSTEDO are contraindicated in patients currently taking tetrabenazine or valbenazine.”
Check it at the source: the deutetrabenazine FDA label on DailyMed (effective February 28, 2025, Teva Neuroscience, Inc.); the valbenazine FDA label on DailyMed (effective April 17, 2026, Neurocrine Biosciences, Inc.).
What does the deutetrabenazine label say about valbenazine?
Deutetrabenazine label, contraindicationsTaking tetrabenazine or valbenazine [see Drug Interactions ( 7.6 )].
Deutetrabenazine label, drug interactionsTetrabenazine or Valbenazine AUSTEDO XR and AUSTEDO are contraindicated in patients currently taking tetrabenazine or valbenazine.
Source: FDA drug label (Austedo), Teva Neuroscience, Inc., effective February 28, 2025 (SPL set 7ea3c60a-45c7-44cc-afc2-d87fa53993c0), via openFDA; the full label on DailyMed
What does the valbenazine label say about deutetrabenazine?
Valbenazine's label (effective April 17, 2026) does not name deutetrabenazine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (INGREZZA), Neurocrine Biosciences, Inc., effective April 17, 2026 (SPL set 4c970164-cafb-421f-9eb5-c226ef0a3417), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Deutetrabenazine | Valbenazine | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $249.32 per unit 12-18-24-30 mg) | $283.32 per capsule 80 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once