Dextromethorphan · more major-labeled pairs than Desvenlafaxine
SPL labels Desvenlafaxine + Dextromethorphan as minor; Desvenlafaxine 13 / Dextromethorphan 11 in that band.
Mechanism on file: Desvenlafaxine does not significantly affect the liver enzymes that process dextromethorphan.
FDA SPL severity: Minor
Desvenlafaxine + Dextromethorphan · SPL mechanism field
Desvenlafaxine does not significantly affect the liver enzymes that process dextromethorphan.
Minor band excerpt · Desvenlafaxine with Dextromethorphan
Examples desipramine, atomoxetine, dextromethorphan, metoprolol, nebivolol, perphenazine, tolterodine 7.2 Drugs Having No Clinically Important Interactions with PRISTIQ Based on pharmacokinetic studies, no dosage adjustment is required for drugs that are mainly metabolized by CYP3A4 (e.g., midazolam), or for drugs that are metabolized by both CYP2D6 and CYP3A4 (e.g., tamoxifen, aripiprazole), when administered concomitantly with PRISTIQ [see Clinical Pharmacology (12.3) ].
Desvenlafaxine · 19 SPL pairs (broader portfolio than Dextromethorphan)
- Aripiprazole minor
- Atomoxetine minor
- Buspirone minor
- Desipramine minor
Dextromethorphan · 1 major-labeled pairs (vs Desvenlafaxine's 0)
- Abiraterone minor
- Aripiprazole minor
- Brexpiprazole minor
- Fluvoxamine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.