What the FDA labels say about taking them together
Desflurane and norepinephrine
Norepinephrine's FDA label of June 12, 2025 names desflurane in its drug interactions section; the desflurane label PlainMeds reads does not name norepinephrine.
Check it at the source: the desflurane FDA label on DailyMed (effective October 14, 2025, Baxter Healthcare Corporation); the norepinephrine FDA label on DailyMed (effective June 12, 2025, Hospira, Inc.).
What does the desflurane label say about norepinephrine?
Desflurane's label (effective October 14, 2025) does not name norepinephrine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (SUPRANE), Baxter Healthcare Corporation, effective October 14, 2025 (SPL set 3fe3d468-d283-4dd0-a1a7-29291a9b2d0b), via openFDA; the full label on DailyMed
What does the norepinephrine label say about desflurane?
Norepinephrine label, drug interactionsConcomitant use of LEVOPHED with halogenated anesthetics (e.g., cyclopropane, desflurane, enflurane, isoflurane, and sevoflurane) may lead to ventricular tachycardia or ventricular fibrillation.
Source: FDA drug label (Norepinephrine Bitartrate, NDA214313), Baxter Healthcare Corporation, effective February 6, 2026 (SPL set 6363e9b4-29df-4553-904d-a563e5adda6e), via openFDA
Source: FDA drug label (Norepinephrine, NDA214628), Long Grove Pharmaceuticals, LLC, effective December 4, 2025 (SPL set 759807dd-61a8-4f6f-8bf5-f6ee773c81bc), via openFDA
Source: FDA drug label (Norepinephrine Bitartrate In Sodium Chloride, NDA215700), WG Critical Care, LLC, effective February 17, 2026 (SPL set ddbef60d-c20a-4ada-928f-e87074c08a54), via openFDA
Source: FDA drug label (LEVOPHED), Hospira, Inc., effective June 12, 2025 (SPL set 2c7dd2b0-cc10-4db6-bf56-6eb154ebeb10), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Desflurane | Norepinephrine | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | A presentation being discontinued | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once