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What the FDA labels say about taking them together

Deferasirox and nisoldipine

Deferasirox's FDA label of January 28, 2026 names nisoldipine in its drug interactions section; the nisoldipine label PlainMeds reads does not name deferasirox. The deferasirox label: “Closely monitor patients for signs of reduced effectiveness when deferasirox is administered with drugs metabolized by CYP3A4.”

Check it at the source: the deferasirox FDA label on DailyMed (effective January 28, 2026, Novartis Pharmaceuticals Corporation); the nisoldipine FDA label on DailyMed (effective March 12, 2026, Covis Pharma US, Inc).

What does the deferasirox label say about nisoldipine?

Deferasirox label, drug interactions

Closely monitor patients for signs of reduced effectiveness when deferasirox is administered with drugs metabolized by CYP3A4 (e.g., alfentanil, aprepitant, budesonide, buspirone, conivaptan, cyclosporine, darifenacin, darunavir, dasatinib, dihydroergotamine, dronedarone, eletriptan, eplerenone, ergotamine, everolimus, felodipine, fentanyl, hormonal contraceptive agents, indinavir, fluticasone, lopinavir, lovastatin, lurasidone, maraviroc, midazolam, nisoldipine, pimozide, quetiapine, quinidine, saquinavir, sildenafil, simvastatin, sirolimus, tacrolimus, tolvaptan, tipranavir, triazolam, ticagrelor, and vardenafil) [see Clinical Pharmacology (12.3)].

Source: FDA drug label (Exjade), Novartis Pharmaceuticals Corporation, effective January 28, 2026 (SPL set 3495a70c-870c-4968-940e-8baea152cf85), via openFDA; the full label on DailyMed

What does the nisoldipine label say about deferasirox?

Nisoldipine's label (effective March 12, 2026) does not name deferasirox in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Sular), NDA020356 (Azurity), as published by Covis Pharma US, Inc, effective March 12, 2026 (SPL set 589157fa-d129-4de3-be3d-e0e1c22c5873), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

20Deferasirox generic labelers
1Nisoldipine generic labelers
DeferasiroxNisoldipine
Labeled forn/aHigh blood pressure
Boxed warningYesNo
Pharmacy cost (NADAC)$1.25 per tablet 360 mg tablet$5.24 per tablet 34 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?