What the FDA labels say about taking them together
Deferasirox and ergotamine
Deferasirox's FDA label of January 28, 2026 names ergotamine in its drug interactions section; the ergotamine label PlainMeds reads does not name deferasirox. The deferasirox label: “Closely monitor patients for signs of reduced effectiveness when deferasirox is administered with drugs metabolized by CYP3A4.”
Check it at the source: the deferasirox FDA label on DailyMed (effective January 28, 2026, Novartis Pharmaceuticals Corporation); the ergotamine FDA label on DailyMed (effective February 25, 2025, Pangea Pharmaceuticals LLC).
What does the deferasirox label say about ergotamine?
Deferasirox label, drug interactionsClosely monitor patients for signs of reduced effectiveness when deferasirox is administered with drugs metabolized by CYP3A4 (e.g., alfentanil, aprepitant, budesonide, buspirone, conivaptan, cyclosporine, darifenacin, darunavir, dasatinib, dihydroergotamine, dronedarone, eletriptan, eplerenone, ergotamine, everolimus, felodipine, fentanyl, hormonal contraceptive agents, indinavir, fluticasone, lopinavir, lovastatin, lurasidone, maraviroc, midazolam, nisoldipine, pimozide, quetiapine, quinidine, saquinavir, sildenafil, simvastatin, sirolimus, tacrolimus, tolvaptan, tipranavir, triazolam, ticagrelor, and vardenafil) [see Clinical Pharmacology (12.3)].
Source: FDA drug label (Exjade), Novartis Pharmaceuticals Corporation, effective January 28, 2026 (SPL set 3495a70c-870c-4968-940e-8baea152cf85), via openFDA; the full label on DailyMed
What does the ergotamine label say about deferasirox?
Ergotamine's label (effective February 25, 2025) does not name deferasirox in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Ergomar Sublingual), Pangea Pharmaceuticals LLC, effective February 25, 2025 (SPL set a9582fdb-7ddd-4f69-aa7a-66247cdb8c92), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Deferasirox | Ergotamine | |
|---|---|---|
| Labeled for | n/a | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $1.25 per tablet 360 mg tablet | $43.46 per tablet 2 mg tablet sublingual |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once