What the FDA labels say about taking them together
Deferasirox and duloxetine
Deferasirox's FDA label of January 28, 2026 names duloxetine in its drug interactions section; the duloxetine labels PlainMeds reads (2) do not name deferasirox. The deferasirox label: “Metabolized by CYP1A2 Deferasirox inhibits CYP1A2 resulting in an increase in CYP1A2 substrate concentration when these drugs are coadministered.”
Check it at the source: the deferasirox FDA label on DailyMed (effective January 28, 2026, Novartis Pharmaceuticals Corporation); the duloxetine FDA label on DailyMed (effective May 14, 2024, SUN PHARMACEUTICAL INDUSTRIES, INC.).
What does the deferasirox label say about duloxetine?
Deferasirox label, drug interactionsMetabolized by CYP1A2 Deferasirox inhibits CYP1A2 resulting in an increase in CYP1A2 substrate (e.g., alosetron, caffeine, duloxetine, melatonin, ramelteon, tacrine, theophylline, tizanidine) concentration when these drugs are coadministered.
Source: FDA drug label (Exjade), Novartis Pharmaceuticals Corporation, effective January 28, 2026 (SPL set 3495a70c-870c-4968-940e-8baea152cf85), via openFDA; the full label on DailyMed
What does the duloxetine label say about deferasirox?
Duloxetine's label (effective May 14, 2024) and its 1 other brand-application label do not name deferasirox in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (DRIZALMA SPRINKLE), SUN PHARMACEUTICAL INDUSTRIES, INC., effective May 14, 2024 (SPL set b41423b8-dfec-4d79-ba3c-e43a87803d85), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Deferasirox | Duloxetine | |
|---|---|---|
| Labeled for | n/a | Depression, Anxiety, Nerve pain and fibromyalgia, Pain |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $1.25 per tablet 360 mg tablet | $0.102 per capsule 30 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once