What the FDA labels say about taking them together
Daunorubicin and doxorubicin
Daunorubicin's FDA label of January 19, 2026 names doxorubicin in its drug interactions section; the doxorubicin labels PlainMeds reads (2) do not name daunorubicin. The daunorubicin label: “Drug Interactions Use of daunorubicin in a patient who has previously received doxorubicin increases the risk of cardiotoxicity.”
Check it at the source: the daunorubicin FDA label on DailyMed (effective January 19, 2026, Hisun Pharmaceuticals USA, Inc.); the doxorubicin FDA label on DailyMed (effective May 5, 2026, Pfizer Laboratories Div Pfizer Inc).
What does the daunorubicin label say about doxorubicin?
Daunorubicin label, drug interactionsDrug Interactions Use of daunorubicin in a patient who has previously received doxorubicin increases the risk of cardiotoxicity.
Daunorubicin label, warningsPre-existing heart disease and previous therapy with doxorubicin are co-factors of increased risk of daunorubicin-induced cardiac toxicity and the benefit-to-risk ratio of daunorubicin hydrochloride therapy in such patients should be weighed before starting daunorubicin hydrochloride.
Source: FDA drug label (Daunorubicin Hydrochloride), Hisun Pharmaceuticals USA, Inc., effective January 19, 2026 (SPL set 9705fa12-499e-41a3-8fb4-f6df0858b851), via openFDA; the full label on DailyMed
What does the doxorubicin label say about daunorubicin?
Doxorubicin's label (effective May 5, 2026) and its 1 other brand-application label do not name daunorubicin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Doxorubicin Hydrochloride), Pfizer Laboratories Div Pfizer Inc, effective May 5, 2026 (SPL set 1fd148fb-0fbc-4b6f-b790-23546fb46a71), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Daunorubicin | Doxorubicin | |
|---|---|---|
| Labeled for | Leukemia, lymphoma and myeloma | Leukemia, lymphoma and myeloma, Breast cancer |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | n/a | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once