What the FDA labels say about taking them together
Dasiglucagon and indomethacin
Dasiglucagon's FDA label of January 1, 2023 names indomethacin in its drug interactions section; the indomethacin labels PlainMeds reads (4) do not name dasiglucagon. The dasiglucagon label: “In patients taking indomethacin, ZEGALOGUE may lose its ability to raise blood glucose or may even produce hypoglycemia.”
Check it at the source: the dasiglucagon FDA label on DailyMed (effective January 1, 2023, Novo Nordisk); the indomethacin FDA label on DailyMed (effective December 19, 2025, Glenmark Pharmaceuticals Inc., USA).
What does the dasiglucagon label say about indomethacin?
Dasiglucagon label, drug interactionsClinical Impact: In patients taking indomethacin, ZEGALOGUE may lose its ability to raise blood glucose or may even produce hypoglycemia.
Source: FDA drug label (Zegalogue), NDA214231 (Zealand Pharma), as published by Novo Nordisk, effective January 1, 2023 (SPL set 14704879-872c-4967-8779-04a3bbdfb4e6), via openFDA; the full label on DailyMed
What does the indomethacin label say about dasiglucagon?
Indomethacin's label (effective December 19, 2025) and its 3 other brand-application labels do not name dasiglucagon in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Indomethacin), Glenmark Pharmaceuticals Inc., USA, effective December 19, 2025 (SPL set f7ed39e2-5431-4e47-935c-c7441d058f94), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dasiglucagon | Indomethacin | |
|---|---|---|
| Labeled for | n/a | Rheumatoid arthritis, Osteoarthritis |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $493.36 per mL 0.6 mg/0.6 mL autoinj | $0.210 per capsule 75 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once