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What the FDA labels say about taking them together

Dasatinib and ritonavir

Ritonavir's FDA label of July 23, 2026 names dasatinib in its drug interactions section; the dasatinib labels PlainMeds reads (3) do not name ritonavir. The ritonavir label: “… decrease in the dosage or an adjustment of the dosing interval of nilotinib and dasatinib may be necessary for patients requiring co-administration with strong CYP3A inhibitors such as NORVIR. …”

Check it at the source: the dasatinib FDA label on DailyMed (effective November 12, 2025, Alembic Pharmaceuticals Limited); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).

What does the dasatinib label say about ritonavir?

Dasatinib's label (effective November 12, 2025) and its 2 other brand-application labels do not name ritonavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (DASATINIB), Alembic Pharmaceuticals Limited, effective November 12, 2025 (SPL set 645fcf26-1b2f-40c5-881b-8effe02defbd), via openFDA; the full label on DailyMed

What does the ritonavir label say about dasatinib?

Ritonavir label, drug interactions

Concomitant Drug Class/Drug Name: Anticancer Agents: abemaciclib, apalutamide, dasatinib, encorafenib, ibrutinib, ivosidenib, neratinib, nilotinib, venetoclax, vinblastine, vincristine; Effect on Concentration of Ritonavir or Concomitant Drug: ↑ anticancer agents ↓ ritonavir #; Clinical Comment: Apalutamide is contraindicated due to potential for loss of virologic response and possible resistance to NORVIR or to the class of protease inhibitors [see Contraindications () ]. Avoid co-administration of encorafenib or ivosidenib with NORVIR due to potential risk of serious adverse events such as QT interval prolongation. …

Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Dasatinib generic labelers
7Ritonavir generic labelers
DasatinibRitonavir
Labeled forLeukemia, lymphoma and myelomaHIV
Boxed warningNoYes
Pharmacy cost (NADAC)$26.46 per tablet 100 mg tablet$0.607 per tablet 100 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?