Skip to main content

What the FDA labels say about taking them together

Dasatinib and imatinib

Dasatinib's FDA label of November 12, 2025 names imatinib in its warnings and precautions section; the imatinib labels PlainMeds reads (3) do not name dasatinib.

Check it at the source: the dasatinib FDA label on DailyMed (effective November 12, 2025, Alembic Pharmaceuticals Limited); the imatinib FDA label on DailyMed (effective September 8, 2026, Apotex Corp).

What does the dasatinib label say about imatinib?

Dasatinib label, warnings and precautions

After 5 years of follow-up in the randomized newly diagnosed chronic phase CML trial in adults (n=258), the following cardiac adverse reactions occurred: cardiac ischemic events (3.9% dasatinib vs 1.6% imatinib), cardiac-related fluid retention (8.5% dasatinib vs 3.9% imatinib), and conduction system abnormalities, most commonly arrhythmia and palpitations (7% dasatinib vs 5% imatinib).

Source: FDA drug label (DASATINIB), Alembic Pharmaceuticals Limited, effective November 12, 2025 (SPL set 645fcf26-1b2f-40c5-881b-8effe02defbd), via openFDA; the full label on DailyMed

What does the imatinib label say about dasatinib?

Imatinib's label (effective September 8, 2026) and its 2 other brand-application labels do not name dasatinib in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Imatinib Mesylate), Apotex Corp, effective September 8, 2026 (SPL set 0291eca5-7a1d-4a79-30be-252224d96509), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Dasatinib generic labelers
20Imatinib generic labelers
DasatinibImatinib
Labeled forLeukemia, lymphoma and myelomaLeukemia, lymphoma and myeloma
Boxed warningNoNo
Pharmacy cost (NADAC)$26.46 per tablet 100 mg tablet$0.624 per tablet 100 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?