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What the FDA labels say about taking them together

Dasatinib and fosamprenavir

Fosamprenavir's FDA label of September 15, 2023 names dasatinib in its drug interactions section; the dasatinib labels PlainMeds reads (3) do not name fosamprenavir. The fosamprenavir label: “Fosamprenavir or fosamprenavir/ritonavir may increase plasma concentrations of antineoplastics metabolized by CYP3A, potentially increasing the risk of adverse events typically associated with these medications. …”

Check it at the source: the dasatinib FDA label on DailyMed (effective November 12, 2025, Alembic Pharmaceuticals Limited); the fosamprenavir FDA label on DailyMed (effective September 15, 2023, Mylan Pharmaceuticals Inc.).

What does the dasatinib label say about fosamprenavir?

Dasatinib's label (effective November 12, 2025) and its 2 other brand-application labels do not name fosamprenavir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (DASATINIB), Alembic Pharmaceuticals Limited, effective November 12, 2025 (SPL set 645fcf26-1b2f-40c5-881b-8effe02defbd), via openFDA; the full label on DailyMed

What does the fosamprenavir label say about dasatinib?

Fosamprenavir label, drug interactions

Concomitant Drug Class/Drug Name: Antineoplastics: Dasatinib, nilotinib, ibrutinib, vinblastine, everolimus; Effect on Concentration of Amprenavir or Concomitant Drug: ↑ Antineoplastics; Clinical Comment: Fosamprenavir or fosamprenavir/ritonavir may increase plasma concentrations of antineoplastics metabolized by CYP3A, potentially increasing the risk of adverse events typically associated with these medications. In case of coadministration, please refer to relevant prescribing information for these medications.

Source: FDA drug label (Fosamprenavir Calcium), Mylan Pharmaceuticals Inc., effective September 15, 2023 (SPL set 3a1424d8-844c-4e24-9ebd-b2c2b61b61a3), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

14Dasatinib generic labelers
2Fosamprenavir generic labelers
DasatinibFosamprenavir
Labeled forLeukemia, lymphoma and myelomaHIV
Boxed warningNoNo
Pharmacy cost (NADAC)$26.46 per tablet 100 mg tabletn/a
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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