What the FDA labels say about taking them together
Darunavir and ticagrelor
Darunavir's FDA label of August 29, 2025 names ticagrelor in its drug interactions section; the ticagrelor label PlainMeds reads does not name darunavir. The darunavir label: “Co-administration of PREZISTA/ritonavir and ticagrelor is not recommended.”
Check it at the source: the darunavir FDA label on DailyMed (effective August 29, 2025, Janssen Products LP); the ticagrelor FDA label on DailyMed (effective May 7, 2026, AstraZeneca Pharmaceuticals LP).
What does the darunavir label say about ticagrelor?
Darunavir label, drug interactionsConcomitant Drug Class Drug Name Examples: Platelet aggregation inhibitor: ticagrelor; Effect on Concentration of Darunavir Or Concomitant Drug: ↑ ticagrelor; Clinical Comment: Co-administration of PREZISTA/ritonavir and ticagrelor is not recommended.
Source: FDA drug label (PREZISTA), Janssen Products LP, effective August 29, 2025 (SPL set 814301f9-c990-46a5-b481-2879a521a16f), via openFDA; the full label on DailyMed
What does the ticagrelor label say about darunavir?
Ticagrelor's label (effective May 7, 2026) does not name darunavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (BRILINTA), AstraZeneca Pharmaceuticals LP, effective May 7, 2026 (SPL set f7b3f443-e83d-4bf2-0e96-023448fed9a8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Darunavir | Ticagrelor | |
|---|---|---|
| Labeled for | HIV | Heart attack and coronary artery disease, Stroke prevention |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $1.16 per tablet 600 mg tablet | $0.253 per tablet 90 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once