What the FDA labels say about taking them together
Darunavir and maraviroc
Darunavir's FDA label of August 29, 2025 names maraviroc in its drug interactions section; the maraviroc label PlainMeds reads does not name darunavir. The darunavir label: “When used in combination with PREZISTA/ritonavir, the dose of maraviroc should be 150 mg twice daily.”
Check it at the source: the darunavir FDA label on DailyMed (effective August 29, 2025, Janssen Products LP); the maraviroc FDA label on DailyMed (effective September 26, 2022, ViiV Healthcare Company).
What does the darunavir label say about maraviroc?
Darunavir label, drug interactionsConcomitant Drug Class Drug Name Examples: maraviroc; Effect on Concentration of Darunavir Or Concomitant Drug: ↑ maraviroc; Clinical Comment: When used in combination with PREZISTA/ritonavir, the dose of maraviroc should be 150 mg twice daily.
Source: FDA drug label (PREZISTA), Janssen Products LP, effective August 29, 2025 (SPL set 814301f9-c990-46a5-b481-2879a521a16f), via openFDA; the full label on DailyMed
What does the maraviroc label say about darunavir?
Maraviroc's label (effective September 26, 2022) does not name darunavir in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (SELZENTRY), ViiV Healthcare Company, effective September 26, 2022 (SPL set 46f30ac5-c96b-429e-976d-8c5ee1c0761b), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Darunavir | Maraviroc | |
|---|---|---|
| Labeled for | HIV | HIV |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $1.16 per tablet 600 mg tablet | $9.15 per tablet 150 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once