What the FDA labels say about taking them together
Darifenacin and ritonavir
Darifenacin's FDA label of February 10, 2026 names ritonavir in its drug interactions section; the ritonavir label PlainMeds reads does not name darifenacin. The darifenacin label: “The daily dose of darifenacin extended-release tablets should not exceed 7.5 mg when co-administered with potent CYP3A4 inhibitors.”
Check it at the source: the darifenacin FDA label on DailyMed (effective February 10, 2026, Torrent Pharmaceuticals Limited); the ritonavir FDA label on DailyMed (effective July 23, 2026, AbbVie Inc.).
What does the darifenacin label say about ritonavir?
Darifenacin label, drug interactionsThe daily dose of darifenacin extended-release tablets should not exceed 7.5 mg when co-administered with potent CYP3A4 inhibitors (for example, ketoconazole, itraconazole, ritonavir, nelfinavir, clarithromycin and nefazadone).
Source: FDA drug label (Darifenacin), Torrent Pharmaceuticals Limited, effective February 10, 2026 (SPL set e84f1ae3-b9a2-4a15-a299-c75373891cc1), via openFDA; the full label on DailyMed
What does the ritonavir label say about darifenacin?
Ritonavir's label (effective July 23, 2026) does not name darifenacin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Norvir), AbbVie Inc., effective July 23, 2026 (SPL set 2849298e-de6e-47bb-8194-56e075b33fc3), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Darifenacin | Ritonavir | |
|---|---|---|
| Labeled for | Overactive bladder | HIV |
| Boxed warning | No | Yes |
| Pharmacy cost (NADAC) | $0.432 per tablet 15 mg tablet | $0.607 per tablet 100 mg tablet |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once