Clarithromycin · more major-labeled pairs than Darifenacin
SPL labels Darifenacin + Clarithromycin as minor; Darifenacin 15 / Clarithromycin 30 in that band.
Mechanism on file: Clarithromycin slows down how fast your body breaks down darifenacin, which can cause the drug to build up to higher levels.
FDA SPL severity: Minor
Darifenacin + Clarithromycin · SPL mechanism field
Clarithromycin slows down how fast your body breaks down darifenacin, which can cause the drug to build up to higher levels.
Minor band excerpt · Darifenacin with Clarithromycin
The daily dose of darifenacin extended-release tablets should not exceed 7.5 mg when co-administered with potent CYP3A4 inhibitors (for example, ketoconazole, itraconazole, ritonavir, nelfinavir, clarithromycin and nefazadone).
Darifenacin · 15 minor + 18 total pairs
- Digoxin minor
- Diltiazem minor
- Duloxetine minor
- Erythromycin minor
Clarithromycin · 16 major-labeled pairs (vs Darifenacin's 0)
- Amlodipine minor
- Apixaban minor
- Aripiprazole minor
- Carbamazepine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.