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What the FDA labels say about taking them together

Dapsone and valganciclovir

Valganciclovir's FDA label of December 8, 2025 names dapsone in its drug interactions section; the dapsone labels PlainMeds reads (3) do not name valganciclovir. The valganciclovir label: “Because of potential for higher toxicity, coadministration with VALCYTE should be considered only if the potential benefits are judged to outweigh the risks.”

Check it at the source: the dapsone FDA label on DailyMed (effective July 20, 2026, Macleods Pharmaceuticals Limited); the valganciclovir FDA label on DailyMed (effective December 8, 2025, H2-Pharma, LLC).

What does the dapsone label say about valganciclovir?

Dapsone's label (effective July 20, 2026) and its 2 other brand-application labels do not name valganciclovir in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Dapsone), Macleods Pharmaceuticals Limited, effective July 20, 2026 (SPL set 839d7440-ba0e-4c56-b648-d374b155cf03), via openFDA; the full label on DailyMed

What does the valganciclovir label say about dapsone?

Valganciclovir label, drug interactions

Name of the Concomitant Drug: Other drugs associated with myelosuppression or nephrotoxicity (e.g., adriamycin, dapsone, doxorubicin, flucytosine, hydroxyurea, pentamidine, tacrolimus, trimethoprim/ sulfamethoxazole, vinblastine, vincristine, and zidovudine); Change in the Concentration of Ganciclovir or Concomitant Drug: Unknown; Clinical Comment: Because of potential for higher toxicity, coadministration with VALCYTE should be considered only if the potential benefits are judged to outweigh the risks.

Source: FDA drug label (Valcyte), NDA021304 (Cheplapharm), as published by H2-Pharma, LLC, effective December 8, 2025 (SPL set 4c517a39-2ded-4c5a-8d56-276853414b31), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

27Dapsone generic labelers
19Valganciclovir generic labelers
DapsoneValganciclovir
Labeled forAcnen/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.664 per gram 5% gel$1.91 per tablet 450 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?