What the FDA labels say about taking them together
Daprodustat and rifampin
Daprodustat's FDA label of August 30, 2023 names rifampin in its drug interactions section; the rifampin label PlainMeds reads does not name daprodustat. The daprodustat label: “CYP2C8 Inducers CYP2C8 inducers (e.g., rifampin) may decrease daprodustat exposure, which may result in loss of efficacy.”
Check it at the source: the daprodustat FDA label on DailyMed (effective August 30, 2023, GlaxoSmithKline LLC); the rifampin FDA label on DailyMed (effective February 11, 2026, Lupin Pharmaceuticals, Inc.).
What does the daprodustat label say about rifampin?
Daprodustat label, drug interactionsCYP2C8 Inducers CYP2C8 inducers (e.g., rifampin) may decrease daprodustat exposure, which may result in loss of efficacy.
Source: FDA drug label (Jesduvroq), GlaxoSmithKline LLC, effective August 30, 2023 (SPL set d82aa06e-5a33-4844-99b7-4701313455a4), via openFDA; the full label on DailyMed
What does the rifampin label say about daprodustat?
Rifampin's label (effective February 11, 2026) does not name daprodustat in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (rifampin), Lupin Pharmaceuticals, Inc., effective February 11, 2026 (SPL set b56004f0-f23d-47f6-80c7-39884fccbccc), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Daprodustat | Rifampin | |
|---|---|---|
| Labeled for | Anemia | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | n/a | $0.679 per capsule 300 mg capsule |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once