What the FDA labels say about taking them together
Dantrolene and droperidol
Droperidol's FDA label of June 8, 2022 names dantrolene in its warnings section; the dantrolene labels PlainMeds reads (3) do not name droperidol. The droperidol label: “Since it may be difficult to distinguish neuroleptic malignant syndrome from malignant hyperpyrexia in the perioperative period, prompt treatment with dantrolene should be considered if increases in temperature, heart …”
Check it at the source: the dantrolene FDA label on DailyMed (effective August 21, 2026, Par Health USA, LLC); the droperidol FDA label on DailyMed (effective June 8, 2022, Hikma Pharmaceuticals USA Inc.).
What does the dantrolene label say about droperidol?
Dantrolene's label (effective August 21, 2026) and its 2 other brand-application labels do not name droperidol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (dantrolene sodium), Par Health USA, LLC, effective August 21, 2026 (SPL set 11689f56-15e0-4350-b53f-ae96e5994fea), via openFDA; the full label on DailyMed
What does the droperidol label say about dantrolene?
Droperidol label, warningsSince it may be difficult to distinguish neuroleptic malignant syndrome from malignant hyperpyrexia in the perioperative period, prompt treatment with dantrolene should be considered if increases in temperature, heart rate or carbon dioxide production occur.
Source: FDA drug label (DROPERIDOL), Hikma Pharmaceuticals USA Inc., effective June 8, 2022 (SPL set d89f33ac-8a6e-49e7-94fb-84e58aad65a8), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Dantrolene | Droperidol | |
|---|---|---|
| Labeled for | Muscle spasms and spasticity | n/a |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.409 per capsule 25 mg capsule | n/a |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once