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What the FDA labels say about taking them together

Dantrolene and desflurane

Desflurane's FDA label of October 14, 2025 names dantrolene in its warnings and precautions section; the dantrolene labels PlainMeds reads (3) do not name desflurane.

Check it at the source: the dantrolene FDA label on DailyMed (effective August 21, 2026, Par Health USA, LLC); the desflurane FDA label on DailyMed (effective October 14, 2025, Baxter Healthcare Corporation).

What does the dantrolene label say about desflurane?

Dantrolene's label (effective August 21, 2026) and its 2 other brand-application labels do not name desflurane in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (dantrolene sodium), Par Health USA, LLC, effective August 21, 2026 (SPL set 11689f56-15e0-4350-b53f-ae96e5994fea), via openFDA; the full label on DailyMed

What does the desflurane label say about dantrolene?

Desflurane label, warnings and precautions

Malignant Hyperthermia: Malignant hyperthermia may occur, especially in individuals with known or suspected susceptibility based on genetic factors or family history. Discontinue triggering agents, administer intravenous dantrolene sodium, and apply supportive therapies.

Source: FDA drug label (SUPRANE), Baxter Healthcare Corporation, effective October 14, 2025 (SPL set 3fe3d468-d283-4dd0-a1a7-29291a9b2d0b), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

10Dantrolene generic labelers
1Desflurane generic labelers
DantroleneDesflurane
Labeled forMuscle spasms and spasticityn/a
Boxed warningYesNo
Pharmacy cost (NADAC)$0.409 per capsule 25 mg capsulen/a
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?