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What the FDA labels say about taking them together

Danazol and insulin glulisine

Insulin glulisine's FDA label of November 25, 2025 names danazol in its drug interactions section; the danazol label PlainMeds reads does not name insulin glulisine. The insulin glulisine label: “Drugs that May Decrease the Blood Glucose Lowering Effect of APIDRA Drugs: Atypical antipsychotics, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, phenothiazine derivatives, progestogens …”

Check it at the source: the danazol FDA label on DailyMed (effective April 30, 2020, Lannett Company, Inc.); the insulin glulisine FDA label on DailyMed (effective November 25, 2025).

What does the danazol label say about insulin glulisine?

Danazol's label (effective April 30, 2020) does not name insulin glulisine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Danazol), Lannett Company, Inc., effective April 30, 2020 (SPL set f2c9b713-aafc-49ca-866e-334d9b5c2e2d), via openFDA; the full label on DailyMed

What does the insulin glulisine label say about danazol?

Insulin glulisine label, drug interactions

Drugs that May Decrease the Blood Glucose Lowering Effect of APIDRA Drugs: Atypical antipsychotics, corticosteroids, danazol, diuretics, estrogens, glucagon, isoniazid, niacin, phenothiazine derivatives, progestogens (e.g., in oral contraceptives), protease inhibitors, somatropin, sympathomimetic agents (e.g., albuterol, epinephrine, terbutaline), and thyroid hormones. Intervention: Dose adjustment and increased frequency of glucose monitoring may be required when APIDRA is coadministered with these drugs.

Source: FDA drug label (Apidra), sanofi-aventis U.S. LLC, effective November 25, 2025 (SPL set e7af6a7a-8046-4fb4-9979-4ec4230b23aa), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

4Danazol generic labelers
0Insulin glulisine generic labelers
DanazolInsulin glulisine
Labeled forn/aType 2 diabetes, Type 1 diabetes
Boxed warningYesNo
Pharmacy cost (NADAC)$2.65 per capsule 200 mg capsule$8.16 per mL 100 unit/mL vial
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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